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Calico cats are always______________

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Calico cats are always______________

(a) Male

(b) Female

(c) Klinefelter

(d) Turner

I got this question in an online quiz.

This intriguing question comes from Dosage Compensation Mechanism for X linked Genes topic in chapter Chromosomes and Sex Determination of Cytogenetics

1 Answer

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Right option is (b) Female

To elaborate: In calico cats there is development of black and orange and white patches. This is possible only when the dominant O allele is turned off in some X chromosome due to dosage compensation. As males have only one X chromosome they are never turned off. Thus, only females show this trait.

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