Question

Only sons of the daughter whose father was NTM will be affected by the disease- fragile X chromosome.

(a) True

(b) False

This question was addressed to me at a job interview.

This intriguing question comes from Dynamic Mutation and Anticipation topic in section Nuclear Export & Post Mendelian Genetics of Cytogenetics

Answer 1

Correct option is (b) False

The explanation: The NTM or non-transmitted males will pass the disease to the daughter who can pass it to both her sons and daughters. It is not like the X linked gene inheritance.