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What is the threshold number of repeats in Huntington’s disease?

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What is the threshold number of repeats in Huntington’s disease?

(a) 15

(b) 27

(c) 36

(d) 42

The question was posed to me in an online quiz.

Question is from Dynamic Mutation and Anticipation topic in division Nuclear Export & Post Mendelian Genetics of Cytogenetics

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Best answer
Correct option is (c) 36

The explanation: If the number of CAG repeats in an individual is below 36 then the person will show normal phenotype. If larger than that then Huntington’s disease will result.

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