Question

Which one of the following describes “double dummy”?

(a) The subjects do not know which study treatment they receive

(b) Patients injected with placebo and active doses

(c) Fake treatment

(d) Signed document of the recruited patient for the clinical trial procedures

This question was addressed to me in final exam.

Query is from Controlled Release Medication in division Controlled Release Medication of Drug Biotechnology

Answer 1

The correct choice is (b) Patients injected with placebo and active doses

Easiest explanation: A form of double-blind study called a “double-dummy” design allows additional insurance against bias or placebo effect. In this kind of study, all patients are given both placebo and active doses in alternating periods of time during the study. The use of a placebo (fake treatment) allows the researchers to isolate the effect of the study treatment.