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Which of the following is a mucoprotective drug?

(a) Cimetidine

(b) Omeprazole

(c) Sucralfate

(d) Misoprostol

This question was posed to me in final exam.

Asked question is from Pharmacotherapy of Peptic Ulcer topic in section Histamine, Bradykinin and their Antagonists, Pharmacotherapy of Gastric Ulcer, Peptic Ulcer of Drug Biotechnology

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Right answer is (c) Sucralfate

Explanation: Ulcer protectives also known as mucoprotective drugs have a natural tendency to get bind with damaged proteins. Such drugs binds with the corroded part of our stomach due to ulcer and form a protective layer around it. Drugs such as sucralfate, Colloidal Bismuth Subricate are mucoprotective drugs. Anti H. pyloric drugs are amoxicillin, tinidazole, and tetracycline.

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