Question

Which of the following can be treated by using loop diuretics?

(a) High altitude sickness and renal disease

(b) Hypertension and hypercalcemia

(c) Glaucoma and epilepsy

(d) Glaucoma and hypercalcemia

This question was posed to me in unit test.

The origin of the question is Diuretics in chapter Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology

Answer 1

Correct answer is (b) Hypertension and hypercalcemia

The best I can explain: Loop diuretics act directly on the ascending limb of the loop of Henle to inhibit sodium and chloride resorption. Edema associated with hepatic or renal disease, control of hypertension, increase renal excretion of calcium in patients with hypercalcemia, useful when rapid diuresis is desired because of the rapid onset of action.