Question

What is the characteristic of encapsulation or coating dissolution-controlled release systems?

(a) Microencapsulation using slowly dissolving materials

(b) Prolonged their residence in the GIT and release

(c) Release only at a specific drug

(d) Employ waxes to control the rate of dissolution

I got this question in a job interview.

My query is from Biopharmaceuticals topic in chapter Biopharmaceuticals of Drug Biotechnology

Answer 1

Correct answer is (a) Microencapsulation using slowly dissolving materials

Best explanation: When drugs are encapsulated with slowly dissolving materials such as that of cellulose, PEG, waxes, etc. The pellets may be filled up in hard gelatin capsules and then compresses to form into tablets. The dissolution rate of the coat depends upon the solubility and thickness of the coat.