Question

What are the characteristics of reservoir devices-controlled release systems?

(a) Release the drug along the entire length of GIT

(b) Drug disperse in the insoluble matrix of rigid hydrophobic materials

(c) Hollow systems containing drug surrounded by a polymer membrane

(d) Employ waxes to control the rate of dissolution

The question was asked during an internship interview.

The question is from Biopharmaceuticals in chapter Biopharmaceuticals of Drug Biotechnology

Answer 1

Right option is (c) Hollow systems containing drug surrounded by a polymer membrane

The explanation: These systems are hollow which contains an inner core of drug surrounded in a water-insoluble polymer membrane. The drug release mechanism involves partitioning into the membrane with subsequent release into the surrounding fluid by diffusion.