Question

Which of the following is a characteristic of resealed erythrocytes?

(a) Nonimmunogenic

(b) Aqueous solutions

(c) Control drug release by partitioning the drug from the oil

(d) Size range 10-100 nm

This question was addressed to me during an interview.

My doubt stems from Biopharmaceuticals in chapter Biopharmaceuticals of Drug Biotechnology

Answer 1

The correct choice is (a) Nonimmunogenic

Best explanation: In this system, the drug is loaded in the body’s own erythrocytes and used to serve as a controlled drug delivery system. These are fully biodegradable, nonimmunogenic. They can circulate transvascularly for days and will allow a large number of drugs to be carried.