Question

Which of the following will be a characteristic of homotypic quaternary structure?

(a) Formed by any single peptide chain in a whole protein molecule

(b) Arrangement of polypeptide chains

(c) Association between identical polypeptides

(d) Association between subunits of different structure

The question was asked in a job interview.

I need to ask this question from Biopharmaceuticals in division Biopharmaceuticals of Drug Biotechnology

Answer 1

Correct answer is (c) Association between identical polypeptides

Easiest explanation: The biological function of some molecules is determined by multiple polypeptide chains. Two kinds of quaternary structures: both are multi-subunit proteins. Homotypic which is an association between identical polypeptide chains. Heterotypic which will be interactions between subunits of very different structures.