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How are OLV liposomes made?

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in Drug Biotechnology by (138k points)
How are OLV liposomes made?

(a) 2-10 bilayers of lipid

(b) Series of concentric bilayers of lipid

(c) A single bilayer of lipid

(d) 100 bilayer of lipid

This question was addressed to me in class test.

Query is from Biopharmaceuticals in section Biopharmaceuticals of Drug Biotechnology

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Correct choice is (a) 2-10 bilayers of lipid

The explanation: OLV is also known as oligolamellar vesicles. These are made up of 2-10 bilayers of lipid surrounding a large internal volume which will be consisting of the drug. MLV is made up of a series of concentric bilayers of lipids. ULV is made of a single layer of lipids. There can be varying sizes from 20-40 nm to 1000 nm.

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