Question

Virus proteins have been expressed in _______________

(a) Bacterial and yeast cells

(b) Yeast and mammalian cells

(c) Mammalian cells

(d) Mammalian, yeast and bacterial cells

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Origin of the question is Immunological Preparations topic in division Immunological Preparations of Drug Biotechnology

Answer 1

Right answer is (d) Mammalian, yeast and bacterial cells

Explanation: Virus proteins have been expressed in bacteria, yeast, mammalian cells, and viruses. This helps in the generation of vaccines. Bacterial cells help in rapid growth and thus the rapid yield of the vaccine. Yeast gives us a post-translational modification. Mammalian cells are hard to culture but some of the proteins can easily be manufactured in mammalian cell culture.