Question

Who invented the process of producing monoclonal antibodies in 1975?

(a) Albert Einstein

(b) Watson and Creek

(c) Georges Köhler and César Milstein

(d) Robert Hook

The question was asked in a national level competition.

This intriguing question comes from Genetic Recombination in chapter Genetic Recombination of Drug Biotechnology

Answer 1

Right option is (c) Georges Köhler and César Milstein

For explanation: The process of producing monoclonal antibodies invented by Georges Köhler and César Milstein in 1975. They shared Nobel Prize in physiology or medicine in 1984 for the discovery. The key idea was to use a line of myeloma cells that had lost their ability to secrete antibodies and come up with a technique to fuse these cells with healthy antibody producing B-cells.