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Why packed bed bioreactors are good?

(a) Does not allow accumulation of products

(b) Allow ease in pH controlling

(c) Allow proper gas distribution

(d) Less concentration of enzymes or cells required because of immobilisation

I got this question in an online interview.

The query is from Antibiotics in section Antibiotics & Enzyme Immobilization of Drug Biotechnology

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The correct option is (a) Does not allow accumulation of products

Explanation: It’s a difficult task to control the pH of packed bed bioreactors by the adding acid or alkali because of poor mixing. These bioreactors are preferred for bioprocessing technology involving product-inhibited reactions since the packed bed bioreactors does not allow accumulation of the products.

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