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Which of the following rRNA molecules have peptidyl transferase activity in prokaryotes?

(a) 23S rRNA

(b) 28S rRNA

(c) 5S rRNA

(d) 18S rRNA

This question was addressed to me in an international level competition.

My question comes from RNA topic in section Biomolecules and Catalysis of Life Sciences

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The correct choice is (a) 23S rRNA

Easiest explanation: rRNA molecules have several roles in protein synthesis, one of them is peptidyl transferase activity. In prokaryotes, 50 subunit has 23S rRNA which has a catalytic role and forms a part of peptidyl transferase activity. Similarly, eukaryotes have 28S rRNA in 60 subunits.

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