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Which of them contains all the information required to fold the polypeptide chain in its 3-D structure?

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Which of them contains all the information required to fold the polypeptide chain in its 3-D structure?

(a) DNA sequences

(b) RNA

(c) Histone protein

(d) Amino acid sequences

The question was posed to me at a job interview.

My doubt stems from Protein Folding topic in section Biomolecules and Catalysis of Life Sciences

1 Answer

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Correct option is (d) Amino acid sequences

For explanation: The native conformation of a protein is determined by its amino acid sequences. This hypothesis was proved by an experiment, in which denaturation followed by renaturation folds the chain in its native structure.

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