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Double-stranded DNA with high GC content has higher thermal stability than that of lower GC content?

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Double-stranded DNA with high GC content has higher thermal stability than that of lower GC content?

(a) True

(b) False

The question was asked in a dream while sleeping

This intriguing question comes from Structure of dsDNA topic in division Biomolecules and Catalysis of Life Sciences

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Best answer
The correct option is (a) True

For explanation I would say: There is three hydrogen bond in G:C while only two between A: T, this shows higher no of hydrogen bonds and interaction in G:C than A:T. Higher G:C content has a higher melting temperature. So, it has more thermal stability as compared to A:T.

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