Question

Which one of the following statement is INCORRECT for Z-DNA?

(a) Left-handed DNA

(b) Mostly found in alternating purine-pyrimidine sequences

(c) Only one deep, narrow groove

(d) Anti glycosidic bond conformation

The question was posed to me in an interview for internship.

This interesting question is from Structure of dsDNA in section Biomolecules and Catalysis of Life Sciences

Answer 1

The correct choice is (d) Anti glycosidic bond conformation

For explanation I would say: Anti glycosidic bond conformation is incorrect as in Z-DNA the sugar and glycosidic bond conformations alternate, anti for C and syn for G while in B form there is only anti glycosidic bond conformation.