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Which of these statements are TRUE for a glycosidic bond?

(a) The bond between sugar and the nitrogenous base

(b) The bond between the two sugar residues

(c) The bond between sugar and phosphate

(d) The bond between base and phosphate

The question was posed to me in a job interview.

This interesting question is from Nucleic Acids topic in portion Biomolecules and Catalysis of Life Sciences

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Right answer is (a) The bond between sugar and the nitrogenous base

Best explanation: The glycosidic bond formed between sugar and nitrogenous base during the formation of a nucleoside. This bond is held to be in β-configuration with respect to the ribose sugar leaving it’s base free to rotate around the bond.

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