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Name the site of pyruvate oxidation.

(a) Cytosol

(b) Mitochondrial matrix

(c) Mitochondrial membrane

(d) Nucleus

I have been asked this question during an interview.

Question is from Respiration in division Bioenergetics and Metabolism of Life Sciences

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Right answer is (b) Mitochondrial matrix

Easy explanation: Pyruvate oxidation takes place in the presence of oxygen inside the mitochondrial matrix and oxidized to acetyl Co-A. Pyruvate is produced in the glycolysis from where it enters to mitochondria with the help of transport protein.

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