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Name the class of MHC which is recognized by CD4 TH cell.

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Name the class of MHC which is recognized by CD4 TH cell.

(a) MHC cannot recognize T cells

(b) MHC III

(c) MHC I

(d) MHC II

I had been asked this question during an interview.

I need to ask this question from Major Histocompatibility Complex topic in chapter Immunology of Life Sciences

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Best answer
The correct choice is (d) MHC II

The best explanation: CD4 is a monomeric single chain which recognizes MHC II molecule and is present on T helper cell. It consists of a core extracellular domain and has three critical serine residues on a cytoplasmic tail.

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