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A certain compound occupied a site Y of an enzyme near to the active site. This immediately resulted in the change of shape of the active site. Y is called a/an ______

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A certain compound occupied a site Y of an enzyme near to the active site. This immediately resulted in the change of shape of the active site. Y is called a/an ______

(a) inactive site

(b) binding site

(c) non-competitive site

(d) allosteric site

I have been asked this question in semester exam.

The doubt is from Drug-Target Interaction topic in portion Chemistry in Everyday Life of Chemistry – Class 12

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Right answer is (d) allosteric site

To elaborate: When a drug binds to an enzyme from a site other than the active site, it is called an allosteric site. Binding to this site causes the change in shape of active site such that the substrate cannot recognise it.

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