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How many genotypes of sickle cell anaemia are possible in a population?

(a) One

(b) Two

(c) Three

(d) Four

I had been asked this question in semester exam.

My question is based upon Inheritance and Variation Principles topic in section Principles of Inheritance and Variation of Biology – Class 12

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The correct choice is (c) Three

Best explanation: Three types of genotypes of sickle cell anaemia are possible in a population. These are:

i. Hb^A Hb^A: Normal individuals

ii. Hb^A Hb^S: Normal individuals but act as a carrier in spreading the disease

iii. Hb^S Hb^S: Diseased individuals and they die before attaining maturity

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