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How are modified genes introduced into the host cells for preparing third-generation vaccines?

(a) Introduced by DNA injection

(b) Introduced by cooling and then icing the cells

(c) Introduced by first giving a heat shock and then cooling the cells

(d) Introduced by making new pathways for pathogens

I had been asked this question in an online interview.

The above asked question is from Human Health and Disease topic in portion Human Health and Disease of Biology – Class 12

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Correct answer is (a) Introduced by DNA injection

To explain: The modified genes are introduced by DNA injection. The host cells read the DNA and synthesise the pathogen’s protein. As these new proteins produced are recognised as foreign, the immune system is alerted and a range of immune responses are triggered.

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