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Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein...

Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein sequences as well.

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asked Sep 10, 2021 in Bioinformatics by nolan (110k points)

Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein sequences as well.

(a) True

(b) False

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My query is from Sequence Homology Versus Sequence Similarity and Identity topic in division Pairwise Sequence Alignment of Bioinformatics

bioinformatics
pairwise sequence alignment
sequence homology versus sequence similarity and identity

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1 Answer

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answered Sep 13, 2021 by myra (687k points)
selected Sep 13, 2021 by nolan

Best answer

Correct answer is (b) False

Easiest explanation: Sequence similarity and sequence identity are synonymous for nucleotide sequences. For protein sequences, however, the two concepts are very different. In a protein sequence alignment, sequence identity refers to the percentage of matches of the same amino acid residues between two aligned sequences. Similarity refers to the percentage of aligned residues that have similar physicochemical characteristics and can be more readily substituted for each other.

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