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When the two sequences have substantial regions of similarity, many dots line up to form contiguous _______ lines.

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When the two sequences have substantial regions of similarity, many dots line up to form contiguous _______ lines.

(a) crossings on

(b) horizontal

(c) diagonal

(d) vertical

I have been asked this question during an interview.

My question is from Methods topic in division Pairwise Sequence Alignment of Bioinformatics

1 Answer

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Best answer
Right choice is (c) diagonal

For explanation: The dots line up to form contiguous diagonal lines, which reveal the sequence alignment. If there are interruptions in the middle of a diagonal line, they indicate insertions or deletions. Parallel diagonal lines within the matrix represent repetitive regions of the sequences.

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