Question

The overall goal of pair wise sequence alignment is to find the best pairing of two sequences, such that there is maximum correspondence among residues.

(a) True

(b) False

The question was asked by my college professor while I was bunking the class.

The above asked question is from Methods topic in section Pairwise Sequence Alignment of Bioinformatics

Answer 1

The correct choice is (a) True

Easy explanation: The goal of pair wise sequence alignment is to find the best pairing and to achieve this goal; one sequence needs to be shifted relative to the other to find the position where maximum matches are found. There are two different alignment strategies that are often used: global alignment and local alignment.