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In a dot matrix, two sequences to be compared are written in the _____________ of the matrix.

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In a dot matrix, two sequences to be compared are written in the _____________ of the matrix.

(a) horizontal and vertical axes

(b) 2 parallel horizontal axes

(c) 2 parallel vertical axes

(d) horizontal axis (one preceding another)

I have been asked this question in an online interview.

This intriguing question comes from Methods topic in section Pairwise Sequence Alignment of Bioinformatics

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The correct option is (a) horizontal and vertical axes

To elaborate: The comparison is done by scanning each residue of one sequence for similarity with all residues in the other sequence. If a residue match is found, a dot is placed within the graph. Otherwise, the matrix positions are left blank.

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