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Which of the following is not true? (a)Paraspeckles are irregular shaped sub-nuclear compartments

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Which of the following is not true?

(a) Paraspeckles are irregular shaped sub-nuclear compartments

(b) Paraspeckles disappear in absence of RNA polemerase II transcription

(c) They are transcription dependent

(d) They are present during interphase and absent during mitosis.

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The query is from Nucleus in chapter Nucleus & Aerobic Respiration of Cell Biology

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Right option is (d) They are present during interphase and absent during mitosis.

Explanation: Paraspeckles are irregular shaped sub-nuclear compartments which are transcription dependent.  Paraspeckles disappear in absence of RNA polemerase II transcription and all of its associated protein components form a crescent shaped perinucleolar cap in the nucleolus. However, paraspeckles are present during the interphase and all the stages of mitosis except the telophase.

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