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Which of the following cellular RNA is not dependent on RanGTP during transport outside nucleus?

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Which of the following cellular RNA is not dependent on RanGTP during transport outside nucleus?

(a) tRNA

(b) rRNA

(c) mRNA

(d) snRNA

The question was posed to me in an internship interview.

This intriguing question comes from Nucleus topic in section Nucleus & Aerobic Respiration of Cell Biology

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The correct option is (c) mRNA

Explanation: All and cellular RNAs such as tRNAs, rRNAs, snRNAs and miRNAs except mRNA are dependent on RanGTP for their transport outside the nucleus. Conserved mRNA export factors such as Mex67/Tap (large subunit) and Mtr2/p15 are required for mRNA transport. In higher eukaryotes, mRNA recruits the protein TREX for spliced mRNA sequences.

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