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Which of the following amino acids does not belong to polar charged group?

(a) Serine

(b) Aspartic acid

(c) Lysine

(d) Arginine

I have been asked this question in an internship interview.

The query is from Chemical Basis of Life in section Chemical Basis of Life of Cell Biology

1 Answer

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Right option is (a) Serine

The explanation: Serine belongs to the category of polar uncharged amino acids whereas aspartic acid, lysine, glutamic acid and arginine belong to polar charged amino acids. These are fully charged at physiological pH and their side chains contain strong organic acids and bases.

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