Question

Which of the following statements about SUPERFAMILY database is incorrect regarding its features?

(a) Sequences can be submitted raw or FASTA format

(b) Sequences must be submitted in FASTA format only

(c) It searches the database using a superfamily, family, or species name plus a sequence, SCOP, PDB or HMM ID’s

(d) It has generated GO annotations for evolutionarily closed domains and distant domains

This question was posed to me during an interview.

The doubt is from Protein Family Databases in chapter Sequence Alignment of Bioinformatics

Answer 1

Correct option is (b) Sequences must be submitted in FASTA format only

Best explanation: SUPERFAMILY is a database of structural and functional annotation for all proteins and genomes. It classifies amino acid sequences into known structural domains, especially into SCOP super families. Sequences can be amino acids, a fixed frame nucleotide sequence, or all frames of a submitted nucleotide sequence. Up to 1000 sequences can be run at a time.