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Use of the dynamic programming method requires a scoring system for the comparison of symbol pairs, and a scheme for GAP penalties.

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Use of the dynamic programming method requires a scoring system for the comparison of symbol pairs, and a scheme for GAP penalties.

(a) True

(b) False

I had been asked this question in homework.

The origin of the question is Dynamic Programming Algorithm for Sequence Alignment topic in division Sequence Alignment of Bioinformatics

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Best answer
The correct answer is (a) True

The best explanation: Once those parameters have been set, the resulting alignment for two sequences should always be the same. Hence, the use of the dynamic programming method requires a scoring system for the comparison of symbol pairs (nucleotides for DNA sequences and amino acids for protein sequences), and a scheme for insertion/deletion (GAP) penalties.

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