Question

Related sequences are identified through the database similarity searching and as the process generates multiple matching sequence pairs, it is often necessary to convert the numerous pair wise alignments into a single alignment.

(a) True

(b) False

The question was posed to me at a job interview.

I want to ask this question from Exhaustive Algorithms topic in section Multiple Sequence Alignment of Bioinformatics

Answer 1

The correct choice is (a) True

The best I can explain: A natural extension of pair wise alignment is multiple sequence alignment, which is to align multiple related sequences to achieve optimal matching of the sequences. Related sequences are identified through the database similarity searching. As the process generates multiple matching sequence pairs, it is often necessary to convert the numerous pair wise alignments into a single alignment, which arranges sequences in such a way that evolutionarily equivalent positions across all sequences are matched.