Question

In the method of extraction of blocks from a global or local MSA, a global MSA of related protein sequences usually includes regions that have been aligned without gaps in any of the sequences.

(a) True

(b) False

I have been asked this question in an interview for internship.

The query is from Localized Alignments in Sequences in section Multiple Sequence Alignment of Bioinformatics

Answer 1

Right answer is (a) True

The best explanation: These ungapped patterns may be extracted from these aligned regions and used to produce blocks. Blocks found in this manner are only as good as the MSA from which they are derived. A global MSA of related protein sequences usually includes regions that have been aligned without gaps in any of the sequences.