Question

Progressive alignment methods use the dynamic programming method to build an MSA starting with the most related sequences and then progressively adding less related sequences or groups of sequences to the initial alignment.

(a) True

(b) False

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The above asked question is from Progressive Methods of Multiple Sequence Alignment in section Multiple Sequence Alignment of Bioinformatics

Answer 1

Right choice is (a) True

Easiest explanation: The progressive alignment methods use the dynamic programming method. Relationships among the sequences are modeled by an evolutionary tree in which the outer branches or leaves are the sequences. The tree is based on pair-wise comparisons of the sequences using one of the phylogenetic methods.