Question

The pattern searching method type of analysis was performed on groups of related proteins, and the amino acid patterns that were located may be found in the Prosite catalog.

(a) True

(b) False

This question was addressed to me in examination.

My doubt stems from Localized Alignments in Sequences in section Multiple Sequence Alignment of Bioinformatics

Answer 1

Correct choice is (a) True

The explanation: This Prosite catalog groups proteins that have similar biochemical functions on the basis of amino acid patterns such as those in the active site. Subsequently, these families were searched for amino acid patterns by the MOTIF program (Smith et al. 1990), which finds patterns of the type aa1 d1 aa2 d2 aa3, where aa1 and aa2 are conserved amino acids and d1 and d2 are stretches of intervening sequence up to 24 amino acids long.