Question

In predicting RNA secondary structure, some simplifying assumptions are usually made, like the _____ structure is similar to the _____

(a) most likely, energetically most unstable structure

(b) most unlikely, energetically most stable structure

(c) most likely, energetically most stable structure

(d) least likely, energetically most stable structure

This question was posed to me by my school principal while I was bunking the class.

My question is from Limitations of Prediction in chapter RNA Structure Prediction of Bioinformatics

Answer 1

The correct answer is (c) most likely, energetically most stable structure

For explanation: The assumption here is that the most predicted or likely structure has to be similar to the energetically most stable structure. The abundance is not taken into consideration in this.