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The HMM is a statistical model that considers few combinations of matches and gaps to generate an alignment of a set of sequences.

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The HMM is a statistical model that considers few combinations of matches and gaps to generate an alignment of a set of sequences.

(a) True

(b) False

The question was posed to me in unit test.

My enquiry is from Iterative Methods of Multiple Sequence Alignment topic in chapter Multiple Sequence Alignment of Bioinformatics

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The correct option is (b) False

The best explanation: The HMM is a statistical model that considers all possible combinations of matches, mismatches, and gaps to generate an alignment of a set of sequences. A localized region of similarity, including insertions and deletions, may also be modeled by an HMM. Analysis of sequences by an HMM is discussed on page 185 along with other statistical methods.

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