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BLASTX uses protein sequences as queries to search against a protein sequence database.

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BLASTX uses protein sequences as queries to search against a protein sequence database.

(a) True

(b) False

The question was posed to me in exam.

I'd like to ask this question from Basic Local Alignment Search Tool (BLAST) in section Database Similarity Searching of Bioinformatics

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Correct choice is (b) False

Explanation: BLASTP, and not BLASTX, uses protein sequences as queries to search against a protein sequence database. BLASTX uses nucleotide sequences as queries and translates them in all six reading frames to produce translated protein sequences, which are used to query a protein sequence database.

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