Question

Which of the following about the Gibbs sampler is untrue?

(a) It is a statistical method for finding motifs in sequences

(b) It is dissimilar to the principle of the EM method

(c) It searches for the statistically most probable motifs

(d) It can find the optimal width and number of given motifs in each sequence

The question was asked in a national level competition.

The above asked question is from Statistical Methods for Aiding Alignment in chapter Multiple Sequence Alignment of Bioinformatics

Answer 1

The correct answer is (b) It is dissimilar to the principle of the EM method

Explanation: It is another statistical method for finding motifs in sequences is the Gibbs sampler. The method is similar in principle to the EM method described above, but the algorithm is different. A combinatorial approach of the Gibbs sampler and MOTIF may be used to make blocks at the BLOCKS Web site.