Question

The use of low-complexity masking in the BLAST procedure means that it may have higher specificity than FASTA because potential false positives are reduced.

(a) True

(b) False

This question was addressed to me in examination.

My question comes from Comparison of FASTA and BLAST in division Database Similarity Searching of Bioinformatics

Answer 1

Right answer is (a) True

Best explanation: In addition to the given statement, BLAST sometimes gives multiple best-scoring alignments from the same sequence. FASTA returns only one final alignment.