Question

In addition to the RNA polymerase, there are also a number of DNA-binding proteins that facilitate the process of transcription.

(a) True

(b) False

The question was asked by my college professor while I was bunking the class.

This interesting question is from Promoter and Regulatory Elements in Prokaryotes & Eukaryotes topic in portion Promoter and Regulatory Element Prediction of Bioinformatics

Answer 1

The correct answer is:

(a) True

In addition to RNA polymerase, there are several DNA-binding proteins that facilitate the process of transcription. These proteins include transcription factors, which help regulate the initiation and efficiency of transcription by binding to specific DNA sequences near the promoter region. In prokaryotes, for example, the sigma factor of RNA polymerase helps initiate transcription, while in eukaryotes, a variety of general transcription factors assist RNA polymerase II in binding to the promoter and initiating transcription. These DNA-binding proteins play essential roles in the regulation of gene expression.