Question

Which of the following is incorrect about Classification of microarray data?

(a) For microarray data, clustering analysis identifies coexpressed and coregulated genes

(b) For microarray data, clustering analysis identifies coexpressed but not coregulated genes

(c) For microarray data, clustering analysis identifies and coregulated but not coexpressed genes

(d) Genes within a category have more similarity in expression than genes from different categories.

I had been asked this question in an internship interview.

I need to ask this question from Microarray-Based Approaches topic in division Functional Genomics & Proteomics of Bioinformatics

Answer 1

Correct option is (a) For microarray data, clustering analysis identifies coexpressed and coregulated genes

To elaborate: When genes are co-regulated, they normally reflect related functionality. Through gene clustering, functions of previously uncharacterized genes may be discovered. Clustering methods include hierarchical clustering and partitioning clustering (e.g., k-means, self-organizing maps [SOMs]).