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which of the following is incorrect about Oligonucleotide Design in A microarray?

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which of the following is incorrect about Oligonucleotide Design in A microarray?

(a) DNA microarrays are generated by fixing oligonucleotides onto a solid support

(b) The oligonucleotide array slide represents thousands of preselected genes from an organism

(c) The length of oligonucleotides is typically in the range of twenty-five to seventy bases long

(d) The oligonucleotides don’t react with cDNA samples

I had been asked this question in final exam.

Query is from Microarray-Based Approaches in division Functional Genomics & Proteomics of Bioinformatics

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The correct option is (d) The oligonucleotides don’t react with cDNA samples

Easy explanation: The oligonucleotides are called probes that hybridize to labeled cDNA samples. Shorter oligo probes tend to be more specific in hybridization because they are better at discriminating perfect complementary sequences fromsequences containing mismatches. However, longer oligos can be more sensitive in binding cDNAs.

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