Question

Which of the following is an incorrect statement about the terminologies related to protein sorting?

(a) Subcellular localization is an integral part of protein functionality

(b) Many proteins exhibit functions only after being transported to certain compartments of the cell

(c) All the proteins exhibit functions after being transported to certain compartments of the cell

(d) Protein sorting is also known as protein targeting

I have been asked this question in an online interview.

This is a very interesting question from Protein Sorting in section Functional Genomics & Proteomics of Bioinformatics

Answer 1

Right choice is (c) All the proteins exhibit functions after being transported to certain compartments of the cell

To explain: The study of the mechanism of protein trafficking and subcellular localization is the field of protein sorting, which has become one of the central themes in modern cell biology. Identifying protein subcellular localization is an important aspect of functional annotation, because knowing the cellular localization of a protein often helps to narrow down its putative functions.