Question

Which of the following is untrue?

(a) MEME is the EM based program only for protein motif discovery

(b) AlignACE is a web-based program using the Gibbs sampling algorithm to find common motifs

(c) AlignACE is optimized for DNA sequence motif extraction

(d) Melina stands for Motif Elucidator In Nucleotide sequence Assembly

I have been asked this question during an interview for a job.

The query is from Prediction Algorithms topic in division Promoter and Regulatory Element Prediction of Bioinformatics

Answer 1

Right choice is (a) MEME is the EM based program only for protein motif discovery

Easiest explanation: The use of MEME is similar to that for protein sequences and DNA motif finding. AlignACE automatically determines the optimal number and lengths of motifs from the input sequences. Melina is a web-based program that runs four individual motif-finding algorithms – MEME, GIBBS sampling, CONSENSUS, and Core search – simultaneously. The user compares the results to determine the consensus of motifs predicted by all four prediction methods.