Question

The all-against-all analyses provide an indication as to the number of protein/gene families in an organism. This number represents the core proteome of the organism from which all biological functions have diversified.

(a) True

(b) False

This question was posed to me in an interview for internship.

Question is from Comparative Genomics topic in chapter Collecting & Storing Sequences in Laboratory of Bioinformatics

Answer 1

Correct option is (a) True

Best explanation: In Hemophilus, 1247 of the total number of 1709 proteins do not have paralogs.

The core proteomes of the worm and fly are similar in size but with a greater number of duplicated genes in the worm. It is quite remarkable that the core proteome of the multicellular organisms (worm and fly) is only twice that of yeast.