Question

The physical contacts between domains are crucial for the functioning of the cellular machinery.

(a) True

(b) False

This question was posed to me in examination.

My question is taken from Protein in division Global Approaches for Studying Protein – Protein Interactions of Bioinformatics

Answer 1

Correct choice is (a) True

Explanation: Interactions between domains occur in multidomain proteins, in stable complexes and in transient interactions between proteins that also exist independently. Experimental approaches for the large-scale determination of protein interactions are emerging. Theoretical analyses based on protein structures have unraveled some of the overall principles and features of the way domains evolved to interact with each other.