Question

Sets of proteins that are part of stable complexes and sets of proteins involved in transient interactions ____ in terms of the similarity in gene expression among the set of proteins.

(a) are similar

(b) differ

(c) are same

(d) show similar function

This question was posed to me by my college director while I was bunking the class.

This question is from Protein in section Global Approaches for Studying Protein – Protein Interactions of Bioinformatics

Answer 1

Correct option is (b) differ

For explanation: Proteins permanently associated in a stable complex need to be present or absent in the cell at the same time. Analysis of microarray data by Gerstein and co-workers by methods along the lines, has shown that the members of stable complexes in the yeast Saccharomyces cerevisiae have highly correlated gene expression patterns.